Alzheimer's Disease Research Center
Alzheimers: Therapy Could Target Blood
31/12/10 11:43 Filed in: Alzheimer's disease research
“ScienceDaily (Dec. 30, 2010) — The aggregated proteins strewn about the brain are the hallmark of one of the most common neurodegenerative disorders: Alzheimer's disease. But while these irregular, gunky proteins, called amyloid-β, are believed to contribute to the deterioration of memory and cognitive ability in Alzheimer's patients, no one knows how they lead to these symptoms, and the severity of the dementia doesn't directly depend on the amount of amyloid-β plaques found in diseased brains.
New experiments from The Rockefeller University, building on a paper published earlier this year, show how amyloid-β interacts with a clotting agent in the blood, increasing blood clots that are harder than usual to break down and starving neurons of their regular supply of oxygen. The research suggests that the effects of amyloid-β on the blood vessels feeding the brain could be an important aspect of the havoc they wreak on the brain.
"There has been a suggestion that vascular dementia and Alzheimer's disease might be related, and our current work provides a possible connection between the two," says Sidney Strickland, head of the Laboratory of Neurobiology and Genetics at Rockefeller....” Read More at Science Daily Read More...
New experiments from The Rockefeller University, building on a paper published earlier this year, show how amyloid-β interacts with a clotting agent in the blood, increasing blood clots that are harder than usual to break down and starving neurons of their regular supply of oxygen. The research suggests that the effects of amyloid-β on the blood vessels feeding the brain could be an important aspect of the havoc they wreak on the brain.
"There has been a suggestion that vascular dementia and Alzheimer's disease might be related, and our current work provides a possible connection between the two," says Sidney Strickland, head of the Laboratory of Neurobiology and Genetics at Rockefeller....” Read More at Science Daily Read More...
Comments
Byrd Alzheimer's Institute Merger with USF Off to Great Start
23/04/10 18:17 Filed in: Alzheimer's disease research | Clinical Trials | Research Grants | Alzheimer's disease treatment
Institute’s merger into USF Health represents “limitless” opportunity for research and treatment.
Some 18 months after the Byrd Institute merged into the USF Health system, three memory clinics are under one roof, as are labs conducting groundbreaking research into the nature of Alzheimer's. Now the Institute's clinicians and researchers are forming seamless teams to treat and someday cure the cruel, crippling and ultimately fatal disease that affects nearly a half-million Floridians. "Overall, it's been a resounding success," said Dr. Stephen K. Klasko, Sr. Vice President for USF Health and Dean of the USF College of Medicine. Achievements Since the Merger Klasko cited a number of achievements since the merger Read More...
